Who says the pick and roll has to be run with the ball handler and only the ball handler? Why can't it be run off-ball? We have two dynamically athletic bigs that are incredible finishers near the rim. Let them PnR for each other. Melo can operate where he's comfortable on the wing. And Tyson and Stat can screen and roll for each other while Melo has the ball. Its already been incorporated some, but I'd like to see it run more as the automatic default. Tyson cross-screens for Stat to get him free near the elbow, where Stat can either sink an easy jumper or explode to the rim, and Chandler can dive off of that into a secondary look for an alley-oop. If its not there, Stat can roll through and set a PnR screen for Melo, while Tyson screen for one of our slashers (JR/Shump/Landry).
I think the idea is to keep them in motion and diving to the rim and then resetting and rescreening. Let them use each other rather than impede each other. Their gift is their athleticism. Keep it in motion. Rather than having them watch Melo and try to figure out where to go to get out of everybody's way. If you don't have the rock, you better be setting a screen or cutting.